Harmonie-Rose Allen, from Bath, graced the nation’s TV screens in the latest series of the award-winning BBC drama.
She featured in the penultimate episode of the sixth series and according to her mum Freya Hall “loved having people fuss over her”, the Bath Chronicle reports.
Freya said: “Harmonie loved it, she didn’t stop smiling.
“She felt like a little celebrity.
“It was just such a fantastic experience. Thank you so very much.”
Harmonie-Rose was close to death in September 2014 when she was struck down with meningococcal septicaemia.
She became a quadruple amputee as doctors stopped the disease from spreading.
A Hope 4 Harmonie campaign, set up following her battle with the disease, raised £240,000 to support her and her family.
Harmonie-Rose was picked up at 6am on the day of filming and driven to the TV studios in Chertsey, Surrey, with her parents.
She met co-stars and fellow amputees Romeo Hadley, five, from Cardiff and Taylor Marshall, two, from Nottingham.
The young trio played victims of Thalidomide, medication that was found to harm the development of unborn babies and cause serious birth defects.
The episode aired on Sunday, March 5.
The production crew treated the families to their very own trailer, a stone’s throw from lead actresses Jenny Agutter, Judy Parfitt, Helen George and Charlotte Ritchie.
Mrs Hall said her daughter really enjoyed dressing up. She said: “She loved having people fuss over her.
Everyone on set was so warm and friendly, showed us so much compassion and was so helpful lugging our luggage around – buggies, bags and toys.
“We will never forget the amazing time we had waiting for our turn to film – in Dr Turner’s lounge no less!”
The tot was signed up by JAM2000 Performing Arts & Agency whose director was full of praise about her personality.
Director Judy McPhee said: “Harmonie is a little delight. She’s very strong willed and absolutely wonderful.
“She’s got the greatest personality and never tires.”