The Liverpool captain is being hampered by a foot problem which has seen him miss successive Premier League matches against Leicester, Arsenal and Burnley, and the midfielder was seen walking with a limp after Sunday’s 2-1 win over the Clarets at Anfield.
Reds manager Jurgen Klopp said Henderson would not be fit for next week’s trip to Manchester City, nor would he be ready to join up with England for the friendly against Germany on March 22 and World Cup qualifier against Lithuania the following week.
“No chance. The break (between games after City) hopefully is two weeks, we hope that will bring him back but there will be no game (for him) in this time,” said Klopp.
“He cannot train, for sure he cannot play against City. It makes sense he is doing the rehab.
“Hopefully he can run in the second week of the international break and then we will have to see.”
The Tottenham striker appeared to roll over his right ankle as he took an early shot in the FA Cup tie.
Kane was under pressure from Lions defender Jake Cooper as he landed before Cristian Eriksen was brought on in the hit man’s place.
Gareth Southgate is set to name his first Three Lions squad since becoming the full-time England boss on Thursday.