Title defenders Madrid comfortably booked their place in the last eight of the competition after beating Napoli 6-2 on aggregate last week.
For Luis Enrique’s men it was an altogether different story as the Catalans overturned a first-leg four-goal deficit to beat Paris Saint-German 6-5 in one of the greatest comebacks in European football.
The story of Barcelona’s incredible comeback
But with Barcelona and Madrid now through to the quarter-finals of the Champions League, there’s every chance the two teams could be drawn against one another.
Should this be the case, Real and Madrid will go head-to-head across two legs in mid-April before then facing off against one another in the league on April 23.
With the quarter-finals of the Champions League set to take place on the 11/12th April, this could see the Clásico played out three times across 11 days.
Such a schedule would be particularly concerning for Zinedine Zidane’s men who host city rivals Atletico the weekend before the quarter-finals.
A similar scenario has played out before. In the 2010/11 season, Barcelona and Madrid met in the semi-finals of the Champions League towards the end of April, from which the Catalans emerged triumphant, having previously played each other 11 days before in La Liga.